Open AccessHemogram components and platelets count variation in anemic patients attending Birat Medical College and Teaching Hospital, Morang, Nepal
Author(s) -
Santosh Upadhyaya Kafle,
Mrinalini Singh,
Neeta Kafle,
Amrita Sinha
Publication year - 2021
Publication title -
journal of pathology of nepal
Language(s) - English
Resource type - Journals
eISSN - 2091-0797
pISSN - 2091-0908
DOI - 10.3126/jpn.v11i1.30385
Subject(s) - medicine , platelet , anemia , hemoglobin , coefficient of variation , gastroenterology , statistics , mathematics
Background: Anemia being the expression of the underlying disease is a global public health problemaffecting both developing as well as developed countries. The RBC indices and platelet count variationamong anemic patients are important to know their association for clinical implications.Materials and Methods: A hospital-based cross-sectional study among anemic patients with hemoglobin<10 gm%, attending Birat Medical College Teaching Hospital, Nepal from 15 May to 15 July 2020 wereanalyzed for RBC indices and platelet count variation. Demographic data, RBC indices, platelet countvariation, and types of anemia were evaluated. Pearson’s correlation coefficient was used for correlatingthe platelet count with RBC indices. A Chi-square test was used to know about the association betweenthe types of anemia and platelet count variation.Results: Out of 150 anemic patients, the female to male ratio was 1.5:1, with the most common agegroup between 40-49 years. There exist high differences between minimum and maximum individualRBC indices (Hb, MCV, MCH, MCH) and platelet count values. The platelet count variation with RBCvalues and MCV had a statistically significant positive and negative correlation respectively. However,the correlation between platelet count variation with hemoglobin concentration level and type of anemiawas positive but statistically not significant.Conclusion: Findings suggest that platelet count variation with RBC indices and types of anemiacorrelated well among anemic patients. Such association will enable the clinicians for diagnosing andtreatment purposes.