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Small cell neuroendocrine carcinoma coexisting with adenocarcinoma of the uterine cervix - a rare entity
Author(s) -
Mukta Meel,
Ankur Jindal,
Mukesh Kumar,
Alka Mittal
Publication year - 2020
Publication title -
journal of pathology of nepal
Language(s) - English
Resource type - Journals
eISSN - 2091-0797
pISSN - 2091-0908
DOI - 10.3126/jpn.v10i2.28736
Subject(s) - parametrium , medicine , adenocarcinoma , cervix , vagina , pathology , small cell carcinoma , carcinoma , clear cell adenocarcinoma , vaginal bleeding , immunohistochemistry , cancer , clear cell , anatomy , pregnancy , biology , genetics
Squamous cell carcinoma and adenocarcinoma are the most common histological types of cervical cancer. The co-existence of two histological types is rare. Here we report a case of a 65-year-old woman with a complaint of postmenopausal bleeding and a history of foul-smelling discharge per vagina for  8  months. On examination cervix flared up with growth, bled on touch, parametrium was involved and adherent anteriorly with bladder & posteriorly with the rectum. Cervical biopsy revealed small cell carcinoma coexisting with Adenocarcinoma. Later it was confirmed by immunohistochemistry.  

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