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Atopic Dermatitis or Hyper IgE Syndrome?
Author(s) -
Muntajibuddin Arif Ahmed,
Ankur Kumar,
Dinesh Raj
Publication year - 2015
Publication title -
journal of nepal paediatric society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.13
H-Index - 8
eISSN - 1990-7982
pISSN - 1990-7974
DOI - 10.3126/jnps.v35i1.11383
Subject(s) - medicine , atopic dermatitis , immunoglobulin e , dermatology , outpatient clinic , immunology , antibody
Eczema and skin infections are commonly encountered in children in the outpatient department. However, presence of both recurrent dermatitis and skin infections should alarm one to consider Hyper IgE syndrome (HIES) as a differential. Here we present a case of HIES in a two and a half year old female child with history of recurrent dermatitis and skin infections in the form of cold abscesses. Laboratory investigations showed markedly elevated IgE levels and high absolute eosinophils counts. Patient was treated with trimethoprim-sulfamethoxazole and supportive care. The current report highlights the fact that HIES can present in early childhood with just skin manifestations and without any significant pulmonary manifestations.J Nepal Paediatr Soc 2015;35(1):59-61

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