Open AccessPhenytoin Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Author(s) -
NK Natt,
S Tarsem,
Anuba,
S Simarjeet,
Manu Sharma,
S Harmanjit
Publication year - 2015
Publication title -
journal of nepal paediatric society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.13
H-Index - 8
eISSN - 1990-7982
pISSN - 1990-7974
DOI - 10.3126/jnps.v35i1.10539
Subject(s) - medicine , rash , eosinophilia , phenytoin , adverse drug reaction , drug reaction , dermatology , adverse effect , drug , drug withdrawal , pediatrics , pharmacology , epilepsy , psychiatry
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare and potentially fatal adverse effect characterized by a skin rash with visceral involvement and haematological abnormalities. This adverse drug effect is often misdiagnosed and under-reported especially in paediatric age group due to its rarity and high occurrence of skin rash in various other viral illnesses of children. We report a case of DRESS in a three months old male child. A high index of suspicion, rapid diagnosis and prompt withdrawal can be life-saving for the patient.J Nepal Paediatr Soc 2015;35(1):73-75