Open AccessmRNA COVID-19 vaccine: A future hope for cancer treatment
Author(s) -
Ajay Kumar Yadav,
Suman Gnawali,
Sandip Kumar Mandal,
Gyan Bahadur Shrestha,
Gangbiao Yuan
Publication year - 2021
Publication title -
journal of biomedical sciences
Language(s) - English
Resource type - Journals
ISSN - 2382-5545
DOI - 10.3126/jbs.v8i2.41959
Subject(s) - vaccination , cancer vaccine , immunization , cancer , medicine , immune system , antigen , cancer immunotherapy , immunotherapy , covid-19 , messenger rna , immunology , virology , cancer research , biology , disease , gene , biochemistry , infectious disease (medical specialty)
Background: mRNA vaccines have a strong potential for a possible cancer therapy platform. They express tumor antigens in antigen-presenting cells (APCs) after immunization, facilitating innate/adaptive immune stimulation. Because of its high effectiveness, safe administration, rapid development potential, and cost-efficient manufacturing, the mRNA cancer vaccine surpasses other traditional vaccination platforms.
Conclusion: Careful evaluation of promising mRNA vaccines to supervise as carriers of lipids for cancer patients needs to be done. In addition, a possible revaluation for optimal protection is required. However, the extent to which solid tumours might take a significant part of the vaccine doses is still unknown.