Open AccessEvaluation of acute oral toxicity of a herbal semen quality enhancer
Author(s) -
SW Hajare,
AUTHOR_ID,
Ranjit Suresh Ingole,
Mahesh Kumar Vitthal Ingawale,
Vivek Borekar,
David Kumar,
Ravikanth Kotagiri,
Bhaskar Ganguly,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID,
AUTHOR_ID
Publication year - 2021
Publication title -
the journal of phytopharmacology
Language(s) - English
Resource type - Journals
ISSN - 2320-480X
DOI - 10.31254/phyto.2021.10611
Subject(s) - toxicity , medicine , acute toxicity , semen , traditional medicine , oral administration , semen quality , physiology , pharmacology , andrology
The objective of this study was to assess the acute oral toxicity of AV/SGB/27 (M/s Ayurvet Limited) in accordance with OECD-423 guideline. AV/SGB/27 is a herbal formulation for enhancing semen quality of livestock. Nine healthy and adult nulliparous nonpregnant Swiss albino female mice, weighing 24-28 g, were used in this study. After being given test material orally, the mice were examined for toxic effects and mortality. Changes in body weights, symptoms of toxicity, histological appearances of liver, kidney, and lungs, and biochemical parameters were used to assess the toxicity. No toxic effects or mortalities were noticed until the trial was completed, indicating that AV/SGB/27 is safe for oral consumption.