Open AccessEvaluation of concurrent exposure of lower concentrations of lead and endosulfan on apoptosis by scatter pattern of flow cytometry
Author(s) -
V. Ranganathan,
Jitendra K. Malik,
G. S. Rao
Publication year - 2021
Publication title -
the journal of phytopharmacology
Language(s) - English
Resource type - Journals
ISSN - 2320-480X
DOI - 10.31254/phyto.2021.10504
Subject(s) - endosulfan , apoptosis , lead acetate , flow cytometry , chemistry , zoology , lead (geology) , splenocyte , toxicology , toxicity , andrology , biology , medicine , immunology , biochemistry , pesticide , paleontology , agronomy , in vitro
The effect of repeated exposure of lower doses of lead and endosulfan were evaluated on apoptosis in male wistar rats. Rats of group I served as untreated control. Group II received drinking water with lead as lead acetate @100 ppm (Pb100). Group III was given feed containing technical grade endosulfan @ 10 ppm (E10). Group IV was exposed to Pb (100) +E (10). Splenocytes were analysed for estimating apoptotic percentage in rats. The results suggest that apoptotic percentage was not changed in the lower doses of endosulfan and lead when administered alone and also in combination in the present study