Open AccessIn vitro anti-coagulant activity of Dalbergia sissoo Bark
Author(s) -
Jyoti B. Wadekar,
Ramesh L. Sawant,
Sachin V Kirtane,
Kunal R Sanklecha,
Amol S Ghodechor,
Bhagyashri B More,
Varsha R Raut
Publication year - 2017
Publication title -
the journal of phytopharmacology
Language(s) - English
Resource type - Journals
ISSN - 2320-480X
DOI - 10.31254/phyto.2017.6508
Subject(s) - dalbergia sissoo , phytochemical , traditional medicine , bark (sound) , anthelmintic , astringent , analgesic , antipyretic , antimicrobial , medicine , pharmacology , chemistry , biology , botany , veterinary medicine , biochemistry , taste , organic chemistry , ecology
Dalbergia sissoo belonging to family Fabaceae is a widely growing plant and has been reported to possess multiple therapeutic properties like analgesic, anti-inflammatory, analgesic and antipyretic anti-ulcer, antioxidant, anthelmintic, antimicrobial, antidiabetic and is also used to treat syphilis, dysentery, nausea, eye and nose disorder, skin diseases and blood disorder. However, the plant yet has not been fully elucidated for its anti-coagulant property. Hence, in the present investigation an attempt has been made to explore the anticoagulant potential of Dalbergia sissoo bark in comparison with a known standard drug as the positive control and normal saline as the negative control. The anti-coagulant activity of the aqueous and alcoholic extract of Dalbergia sissoo bark may be due to presence of phytochemicals such as flavonoids and phenolic compounds which reveals on preliminary phytochemical screening.