Analgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract | Zendy

Wilson Rwai Wawer | Zendy; Lawrence Obado Osuwat | Zendy; Connie Wambui Mureithi | Zendy

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Analgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract

Author(s) -

Wilson Rwai Wawer,

Lawrence Obado Osuwat,

Connie Wambui Mureithi

Publication year - 2017

Publication title -

the journal of phytopharmacology

Language(s) - English

Resource type - Journals

ISSN - 2320-480X

DOI - 10.31254/phyto.2017.6105

Subject(s) - licking , analgesic , anti inflammatory , traditional medicine , chemistry , pharmacology , medicine

Objective: The present study sought to evaluate the anti-inflammatory and analgesic activities of ethanolic extract from Tradescantia fluminensis leaves. Methods: The crude leaf extract of T. fluminensis was investigated for anti-inflammatory and analgesic activities in Wistar Albino rats and mice respectively. The anti-inflammatory activity was investigated using egg albumin induced oedema model while acetic acid and formalin-induced paw licking models were used to evaluate the analgesic activity. Results: The extract showed a significant (P<0.05) dose-dependent inhibition of inflammation and pain compared to the control group. Conclusion: The leaf extract possesses anti-inflammatory and analgesic activities. The activities could be attributed to phytochemicals present in the plant.

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