Open AccessAnalgesic and anti-Inflammatory activity of Tradescantia fluminensis leaves extract
Author(s) -
Wilson Rwai Waweru,
Lawrence Obado Osuwat,
Connie Wambui Mureithi
Publication year - 2017
Publication title -
the journal of phytopharmacology
Language(s) - English
Resource type - Journals
ISSN - 2320-480X
DOI - 10.31254/phyto.2017.6105
Subject(s) - licking , analgesic , anti inflammatory , traditional medicine , chemistry , pharmacology , medicine
Objective: The present study sought to evaluate the anti-inflammatory and analgesic activities of ethanolic extract from Tradescantia fluminensis leaves. Methods: The crude leaf extract of T. fluminensis was investigated for anti-inflammatory and analgesic activities in Wistar Albino rats and mice respectively. The anti-inflammatory activity was investigated using egg albumin induced oedema model while acetic acid and formalin-induced paw licking models were used to evaluate the analgesic activity. Results: The extract showed a significant (P<0.05) dose-dependent inhibition of inflammation and pain compared to the control group. Conclusion: The leaf extract possesses anti-inflammatory and analgesic activities. The activities could be attributed to phytochemicals present in the plant.