Open AccessAnxiolytic activity of ethanolic extract of aerial parts of Tribulus terrestris in mice
Author(s) -
Huda Kafeel,
Ramsha Rukh
Publication year - 2015
Publication title -
the journal of phytopharmacology
Language(s) - English
Resource type - Journals
ISSN - 2320-480X
DOI - 10.31254/phyto.2015.4104
Subject(s) - tribulus terrestris , indian subcontinent , traditional medicine , anxiolytic , anxiety , medicine , pharmacology , biology , traditional chinese medicine , ancient history , history , psychiatry , alternative medicine , pathology
Herbs have always been a preferred choice of treatment for people of the subcontinent and the Indo-Pak subcontinent has a long tradition of the use of herbs as medicines. In the given study ethanolic extract of Tribulus terrestris (EETT) has been screened for its anxiolytic potential in experimental mice using LDB, EPM and Head Dip models of anxiety. It showed an increase in the number of entries and time spent in the light compartment in LDM model. Further time spent in Open Arm has also been significantly increased with p<0.05 in comparison with a control group in EPM apparatus. Increase number of head dips are also suggestive of the possible anxiolytic potential of EETT.