Open AccessPrevalence of irregular antibodies in blood donors at Yaoundé Central Hospital, Cameroun
Author(s) -
Ngo Sack Françoise,
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Essomba Zanga Gilbert Justin,
Chetcha Tchemegni Bernard,
George Mondinde Ikomey,
Ngabengono Pauline,
Tayou Claude,
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Publication year - 2021
Publication title -
journal of medical research
Language(s) - English
Resource type - Journals
ISSN - 2395-7565
DOI - 10.31254/jmr.2021.7603
Subject(s) - medicine , antibody , blood transfusion , population , immunology , autoantibody , blood grouping , blood units , abo blood group system , environmental health
Blood transfusion is a therapy that presents immunological risks due to the possible presence of irregular antibodies in donor or recipient blood. It is therefore recommended to reseaech irregular antibodies in both donors and recipients’ blood during pre-transfusional tests. Data relating to the search for irregular antibodies being scarce in our country, we carried out a cross-sectional descriptive study in blood donors at the Yaoundé central hospital. We recruited 200 blood donors on whose samples we performed blood grouping, screening for irregular antibodies and self-testing. Our study population consisted of 152 men and 48 women; the average age was 27.3 years. As a result, we found 4.5% alloantibodies and 0.5% autoantibodies, so an overall frequency of 5% in irregular antibodies in blood donors. This frequency of alloantibodies supports the systematisation of the Irregular Antibody Test (IAT) in blood banks.