Open AccessDynamic characteristic of SARS-CoV-2 and its antibody detection
Author(s) -
Bahrul Fikri,
Andi Dwi Bahagia Febriani,
Muhamad Ali,
Nasrum Massi
Publication year - 2021
Publication title -
journal of medical research
Language(s) - English
Resource type - Journals
ISSN - 2395-7565
DOI - 10.31254/jmr.2021.7401
Subject(s) - covid-19 , turnaround time , point of care , medicine , virology , point of care testing , antibody , diagnostic test , immunology , computer science , emergency medicine , pathology , disease , outbreak , infectious disease (medical specialty) , operating system
To prevent excess morbidity and mortality of Covid-19, a prompt and accurate diagnosis is crucial. Antibody-based rapid diagnostic test (RDT) is a rapid, fairly reliable, and useful diagnostic testing solution for COVID-19. As a point-of-care test with fast turnaround time, the kit permits quick screening in hospitals to avoid the crowding of specimen collection. However, available RDTs kits have different sensitivity, specificity, and accuracy profiles due to antigen and antibody variability because of the sequence mutation of the SARS-CoV-2 gene. Therefore, it is strongly recommended to either re-measure the accuracy of a rapid test before using it in a different country or use tests developed based on local viral characteristics