A Rare Case report of Ichthyosis Follicularis, Alopecia and Photophobia (IFAP) Syndrome with developmental cataract

Purpose: The IFAP syndrome is a rare X-linked genetic disorder with only 40 reported cases worldwide. We report a 23 year old, male patient with classical IFAP syndrome. Method: Descriptive single case report. Case: 23 years old male patient, presented with ocular findings of photophobia, cornealinfiltrate, superior corneal vascularization and astigmatism along with dermatological manifestations. Result: Photophobia was pathognomonic in a patient presenting with Icthyosisfollicularis and alopecia. Associated ocular findings were corneal infiltrate, superior corneal vascularization, angio regression with pericytic infilterate and Astigmatism. Our patient also presented with bilateral developmental cataract. Conclusion: Developmental cataract can be a primary manifestation with IFAP syndrome. Corneal infiltrates with photophobia as the only presenting symptom can be a rare finding associated with rare skin disorders like IFAP syndrome. They are also the most challenging symptoms to manage.