Open AccessIn-silico studies in herbal drugs: A review
Author(s) -
M Monisha,
Abhaya Kumar Mishra,
Ramesh N V,
K Unnikrishna Pillai,
Vineeth P K
Publication year - 2018
Publication title -
journal of ayurvedic and herbal medicine
Language(s) - English
Resource type - Journals
ISSN - 2454-5023
DOI - 10.31254/jahm.2018.4109
Subject(s) - in silico , computer science , drug , drug discovery , data science , computational biology , data mining , bioinformatics , medicine , pharmacology , biology , gene , biochemistry
Bioinformatics is the latest technology in the research field. In-silico studies are done to identify the exact target of the drug. Which finds a drug for the particular binding site and final stage animal testing can be done for obtaining a conform result. Reviews of in-silico studies in herbal drugs were retrieved through the use of PubMed. Specific software on a computer allows researchers to analyse enormous data without actually conducting a large number of experiments. It helps to give the existing information to model disease pathway and identifies precise targets of the selected drugs. Modern instrumental techniques like XRD, XRF, ICP-MS etc. help in quantitative and qualitative estimation of metals and minerals and structural analysis of compound drugs. A later stage in vivo and in vitro studies can be done for obtaining the confirmatory result.