Review on Trisama- an unexplored ancient ayurvedic formulation

Indian system of medicine has a longstanding history of using medicinal plants for the prevention and treatment of various health ailments. Trisama is an ancient Ayurvedic preparation can be prescribed for a wide range of disorder but not popular as many other Ayurvedic herbal formulations. Trisama is preparing by mixing the Sunthi (Zingiber officinale Linn.), Haritaki (Terminalia chebula Retz.), and Guduchi (Tinospora cordifolia Willd Meirs) in equal proportion. It is credited with diverse beneficial therapeutic effects mainly as Shothhara and Amapachana and reported to possess many pharmacological properties due to its common Usna Virya and Madhur Vipaka of the individual ingredients. The reported pharmacological effects of its ingredients are anti-oxidant, anti-inflammatory, anti-pyretic, analgesic, antimicrobial, hypolipidemic, cardioprotective, gastroprotective, cytoprotective effects etc. The bioactive components responsible for these therapeutic potential are mainly due to the presence of major important phytoconstituents such as phenolics components like gingerols, gingerdiols and gingerdione, shogaols, zingiberine, giloin, berberine, tinosporin, tinosporin acid and gallic acid. The present review focuses on summarizing the formulation details by their Ayurvedic properties, phytoconstituents and pharmacological activity. The review suggests that, Trisama formulation is easily available, economical, palatable and more beneficial for human health.Hence, it may be popularize among general Practitioner as an important Ayurvedic medicine in the form of churna (powder) and kwatha (decoction) for the treatment of Sotha and metabolic disorders.