Open AccessIn vitro antioxidant activity and polyphenol estimation of methanolic fruit extract of Carissa spinarum L.
Author(s) -
A Venkatachalapathi,
Abdul Kaffoor H,
S. Paulsamy
Publication year - 2017
Publication title -
journal of ayurvedic and herbal medicine
Language(s) - English
Resource type - Journals
ISSN - 2454-5023
DOI - 10.31254/jahm.2017.3304
Subject(s) - dpph , abts , chemistry , antioxidant , radical , polyphenol , hydroxyl radical , traditional medicine , food science , organic chemistry , medicine
Antioxidant property of methanolic fruit extract of the medicinal tree species, Carissa spinarum was evaluated by studying the contents of total phenolics, tannins and flavonoids, free radical scavenging activity using 1,1-diphenyl-2- picryl hydrozyl (DPPH), hydroxyl radical scavenging activity, reducing power activity, ABTS•+ assay and metal chelating activity. The results of the study revealed that both the parts studied were found to have potent antioxidant activity against DPPH, hydroxyl and ABTS•+ radicals with the IC50 value of 88.98 for methanolic fruit extract for DPPH radicals and 849.70 for hydroxyl radicals. Therefore methanolic fruit extract of C. spinarum can be considered as a new potential source of natural antioxidants for pharmaceutical industries.