Open AccessFeatures of hepatobiliary system function in biliary dyskinesia in children with type 1 diabetes mellitus
Author(s) -
И. Ю. Мельникова,
Vladimir N. Buryak,
N. I. Shaban
Publication year - 2022
Publication title -
èksperimentalʹnaâ i kliničeskaâ gastroènterologiâ
Language(s) - English
Resource type - Journals
ISSN - 1682-8658
DOI - 10.31146/1682-8658-ecg-197-1-38-44
Subject(s) - medicine , dyskinesia , hemodynamics , diabetes mellitus , blood flow , gastroenterology , artery , biliary dyskinesia , cardiology , endocrinology , cholecystectomy , disease , parkinson's disease
A study of intrahepatic hemodynamics was conducted in 150 children aged 11 to 14 years, of which 33 were practically healthy children, 117 were patients with biliary dyskinesia (85 with type 1 diabetes, 32 without type 1 diabetes). In patients with biliary dyskinesia, a decrease in the speed of blood flow in the hepatic artery with an increase in indices (resistance, pulsation, systolic-diastolic), as well as an increase in the speed of blood flow in the hepatic vein with a decrease in these indices was revealed. The inhibition of hepatic hemodynamics may be due to the deterioration of bile secretion, as a result of a violation of the normal innervation of the bile system, associated with the development of diabetic neuropathy in children with type 1 diabetes. It is suggested that angiopathy of hepatic arteries and veins plays a certain role in the Genesis of intrahepatic blood flow disorders.