Open AccessDiagnostics of the Small Intestinal Bacterial Overgrowth Syndrome
Author(s) -
R. Plavnik,
Е. В. Тиванова,
V. I. Nevmerzhitsky,
Т Э Плавник,
L. I. Gubaydulina,
М. А. Калашникова,
A. O. Eletskaja,
E. V. Jastrebova,
T. A. Batyukhno
Publication year - 2022
Publication title -
èksperimentalʹnaâ i kliničeskaâ gastroènterologiâ
Language(s) - English
Resource type - Journals
ISSN - 1682-8658
DOI - 10.31146/1682-8658-ecg-196-12-15-20
Subject(s) - small intestinal bacterial overgrowth , medicine , gastroenterology , hydrogen breath test , bacterial overgrowth , breath test , feces , diagnostic test , irritable bowel syndrome , veterinary medicine , microbiology and biotechnology , helicobacter pylori , biology
The Small Intestine Bacterial Overgrowth syndrome ( SIBO) is a widespread pathology both independently and in combination with other diseases of the gastrointestinal tract, therefore, its timely and accurate diagnosis remains a very urgent task. Aim . Purpose of the study: comparative assessment of the diagnostic information content of two methods for diagnosing SIBO—hydrogen-methane breath test (HMBT) and stool analysis for short-chain fatty acids (SCFA). Material and Methods : 65 patients aged from 18 to 76 years were examined. 40 made up the main group, with clinical symptoms of SIBO, and 25—the control group. All patients underwent HMBT with the «SIBRTEST» test kit and stool analysis for SCFA. For both tests, diagnostic sensitivity, specifi city, and accuracy were calculated and comparatively evaluated. Results : HMBT showed sensitivity 90.24%, specifi city 95.83%, accuracy 92.3%. The analysis of feces for SCFA showed, respectively, a sensitivity of 90.24%, a specifi city of 50.0% and an accuracy of 75.38%. Conclusion : HMBT with the SIBRTEST test kit can be recommended in the diagnosis of SIBO. The SCFA test should be treated with caution due to the high probability of false positive results.