Open AccessA practical case: features of the autoimmune insulin syndrome diagnosis
Author(s) -
Natalia Zykova,
E. V. Ignashina,
E. D. Li,
V. V. Kugryshev
Publication year - 2022
Publication title -
èksperimentalʹnaâ i kliničeskaâ gastroènterologiâ
Language(s) - English
Resource type - Journals
ISSN - 1682-8658
DOI - 10.31146/1682-8658-ecg-195-11-100-103
Subject(s) - medicine , disease , hyperinsulinemic hypoglycemia , hypoglycemia , autoantibody , insulin , autoimmune disease , diabetes mellitus , immunology , intensive care medicine , endocrinology , antibody
Autoimmune Insulin syndrome (AIS), also named Hirata disease, is a rare condition characterized by hypoglycemic episodes due to the presence of high titers of insulin autoantibodies (IAA). AIS is a form of immune-mediated hypoglycemia, which develops when a triggering factor (medication or a viral infection) acts on an underlying predisposing genetic background. The diagnosis of IAS is challenging, requiring a careful workup aimed at excluding other causes of hyperinsulinemic hypoglucemia. The article presents a case of Hirata disease diagnosing of a patient of the therapy department of the Multidisciplinary Medical Center of the Bank of Russia. Purpose : Determining of the features of the diagnosis of Autoimmune Insulin syndrome (Hirata disease) Materials and methods : the article presents a clinical case of the diagnosis of Autoimmune insulin syndrome (Hirata disease), focuses on the diagnostic signicance of laboratory tests. The article is intended for general practitioners, endocrinologists, gastroenterologists.