Open AccessDiagnosis of promicrolithic changes in gallbladder bile by crystallography
Author(s) -
Я. М. Вахрушев,
Н. А. Хохлачева,
Н. Н. Глазырина,
А. М. Фаррахов
Publication year - 2021
Publication title -
èksperimentalʹnaâ i kliničeskaâ gastroènterologiâ
Language(s) - English
Resource type - Journals
ISSN - 1682-8658
DOI - 10.31146/1682-8658-ecg-189-5-12-18
Subject(s) - medicine , gallbladder , stage (stratigraphy) , ultrasound , gastroenterology , gallbladder disease , radiology , paleontology , biology
The aim of the study. Determining the dependence of the bile microstructure degree of destabilization of bile and on the age of patients with the I (pre-stone) stage of the cholelitiasis. Material and methods. About 396 patients with stage I of cholelitiasis. 1 group consisted of 125 young patients (25–44 years), 2 groups — 164 middle-aged patients (45–59 years), 3 group — 107 elderly patients (60–74 years). In verifi cation of the diagnosis, in addition to anamnestic and general clinical data, the results of ultrasound examination (ultrasound) of the gallbladder, the study of the physical and chemical properties of bile are used. Crystallography was used to study the morphological pattern of the gallbladder. Results. In the evaluation of the bladder bile of patients with stage I gallstone disease, there is a decrease in the angle of the tilt of the liquid crystal lines, as well as the appearance of optically active inclusions, such as branched dendrites with plate branches, matted- fi ber aggregates, shield- shaped units and short- branched dendrites. Conclusion. Crystallography is highly sensitive, but at the same time an easy-to-perform method and can be widely used in early diagnosis of gallstone disease.