Open AccessIncreased ammonia levels and its association with visceral obesity and insulin resistance
Author(s) -
Г. В. Шавкута,
T. V. Shnyukova,
Э. С. Колесникова,
Vladimir Kruchinin,
A. K. Lyutova,
А. С. Тимченко
Publication year - 2020
Publication title -
èksperimentalʹnaâ i kliničeskaâ gastroènterologiâ
Language(s) - English
Resource type - Journals
ISSN - 1682-8658
DOI - 10.31146/1682-8658-ecg-169-9-75-79
Subject(s) - hyperammonemia , insulin resistance , medicine , endocrinology , carbohydrate metabolism , steatosis , obesity , metabolic syndrome , metabolism , insulin
Hyperammonemia is considered as a significant trigger factor in the progression of liver diseases, starting from the stage of steatosis. There is also a link between high levels of ammonia and metabolic syndrome. The article discusses the relationship of hyperammonemia with a violation of carbohydrate metabolism. It is likely that an increase in ammonia is associated with an increase in visceral fat and may be a predictor of the development of insulin resistance as a key factor in carbohydrate metabolism disorders.