Open AccessExpression of cytochrome P450 and MDR1 in patients with proctitis
Author(s) -
Magnus Thörn,
Niklas Finnström,
Stefan Lundgren,
Anders Rane,
Lars Lööf
Publication year - 2007
Publication title -
upsala journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.808
H-Index - 41
eISSN - 2000-1967
pISSN - 0300-9734
DOI - 10.3109/2000-1967-203
Subject(s) - medicine , cyp3a5 , cyp3a4 , proctitis , gene expression , intestinal mucosa , inflammation , gastroenterology , lamina propria , gene , pathology , microbiology and biotechnology , cytochrome p450 , epithelium , ulcerative colitis , genotype , biology , metabolism , biochemistry , disease
The aim of this study was to investigate the effect of inflammation on the gene expression of three cytochrome P450's (CYP) and P-glycoprotein (P-gp) in the rectal and colonic mucosa in patients with proctitis.