Increased Serum Concentrations of Carbohydrate-Deficient Transferrin (CDT) in Patients with Cystic Fibrosis | Zendy

Anders Larsson | Zendy; Mats Flodin | Zendy; H Kollberg | Zendy

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Increased Serum Concentrations of Carbohydrate-Deficient Transferrin (CDT) in Patients with Cystic Fibrosis

Author(s) -

Anders Larsson,

Mats Flodin,

H Kollberg

Publication year - 1998

Publication title -

upsala journal of medical sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.808

H-Index - 41

eISSN - 2000-1967

pISSN - 0300-9734

DOI - 10.3109/03009739809178952

Subject(s) - carbohydrate deficient transferrin , medicine , transferrin , cystic fibrosis , glycosylation , alcohol abuse , carbohydrate , alcohol consumption , gastroenterology , endocrinology , alcohol , biochemistry , psychiatry , biology

Carbohydrate-deficient transferrin (CDT) has been reported to be one of the best laboratory markers in serum (S) for detection of alcohol abuse. We have studied S-CDT values in cystic fibrosis (CF) patients and show that CF patients have increased S-CDT values without high alcohol consumption. CF patients have abnormalities in their protein glycosylation and sialylation, which may explain the increased S-CDT values.

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