Open AccessJet Expulsion of Cellular Contents from Red Cells during Photodynamic Hemolysis
Author(s) -
N. V. B. Marsden,
A. M. M. ZadeOppen,
H. G. Davies
Publication year - 1981
Publication title -
upsala journal of medical sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.808
H-Index - 41
eISSN - 2000-1967
pISSN - 0300-9734
DOI - 10.3109/03009738109179204
Subject(s) - hemolysis , medicine , rose bengal , contraction (grammar) , biophysics , hemoglobin , biology , genetics
When red cells are incubated in the dark in the presence of the dye Rose Bengal and subsequently irradiated with visible light, they hemolyze. Under certain conditions some of the hemoglobin is expelled in the form of a convective jet and appears as a transient cloud beside the cell. Elastic contraction of the membrane is not a sufficient driving force for the jet. A plausible mechanism (an osmotic "pump") is presented.