Open AccessOvarian hyperstimulation syndrome (OHSS) in pregnancy not associated with ovulation induction
Author(s) -
Regi Annie,
Mathai Matthews,
Jasper Padmini,
Krishnaswami Hemalatha,
Prem Suneeta,
Peedicayil Abraham
Publication year - 1996
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349609054680
Subject(s) - ovarian hyperstimulation syndrome , medicine , oliguria , pregnancy , ovulation induction , polycystic ovarian disease , gynecology , obstetrics , in vitro fertilisation , ovulation , endocrinology , diabetes mellitus , polycystic ovary , hormone , insulin resistance , genetics , renal function , biology
Ovarian hyperstimulation syndrome (OHSS) has gained recent interest because of various ovarian stimulation regimes used for treatment of infertility (1). Ovarian hyperstimulation syndrome is commonly associated with disorders of pregnancy with high levels of serum hCG such as gestational trophoblastic disease, fetal hydrops, multifetal gestation in late months of pregnancy, and conditions associated with large placentae such as diabetes and Rhesus isoimmunization (2). It is very rarely seen in pregnancy where ovulatory drugs or hormones have not been used (3). Oligomenorrhoic anovulation and low age and low weight are other risk factors (4). Ovarian hyperstimulation syndrome is characterized by extremely enlarged ovaries with multiple cysts, increased capillary permeability and loss of fluid and proteins from the intravascular to extravascular space. Clinically OHSS is associated with hypovolemia, oliguria, ascites, abdominal pain, pleural effusion, hemoconcentration and electrolyte imbalances, especially hyperkalemic acidosis (5).