Open AccessOral poliovirus vaccination and pregnancy complications
Author(s) -
HarjulehtoMervaala Tina,
Hovi Tapani,
Aro Timo,
Saxen Harri,
Hiilesmaa Vilho K.
Publication year - 1995
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349509024446
Subject(s) - medicine , pregnancy , vaccination , poliovirus , poliomyelitis , polio vaccination , obstetrics , gynecology , pediatrics , virus , immunology , genetics , biology
Background. To determine whether the effect of live attenuated oral polio virus vaccine given to pregnant women increases pregnancy complications. Methods. A study of women who had been vaccinated against poliovirus during a national vaccination campaign and who had delivered by cesarean section in three obstetrical hospitals in southern Finland. One thousand seven hundred and forty‐seven vaccinated women (in three study cohorts), and their 2293 nonvaccinated controls (in two reference cohorts) were analyzed. Subjects are out of 22 000 deliveries evaluated earlier. Results. Vaccinated sectioned women did not show an excess of pregnancy complications. The mean rate of cesarean sections was 18.4% in the study cohorts and 18.9% in the reference cohorts counted from the 22 000 deliveries. Conclusions. Oral live attenuated polio virus vaccine does not increase pregnancy complications and is considered a safe alternative for vaccinating pregnant women.