Open AccessComputerized colposcopy and conservative management of cervical intraepithelial neoplasia in pregnancy
Author(s) -
Mikhail Magdy S.,
Anyaegbunam Akolisa,
Romney Seymour L.
Publication year - 1995
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349509024432
Subject(s) - colposcopy , medicine , cervical intraepithelial neoplasia , pregnancy , biopsy , gestation , obstetrics , gynecology , radiology , cervical cancer , cancer , biology , genetics
Background. Computerized colposcopy is the noninvasive digital processing of colposcopic images acquired using a charge‐coupled device camera. The purpose of this study was to evaluate the clinical applications of computerized colposcopy, and to record the colposcopic changes associated with progression or regression of cervical intraepithelial neoplasia in pregnancy. Methods. Forty‐one pregnant patients, with abnormal Papanicolaou smears and a fully visualized squamo‐columnar junction, were serially monitored throughout their pregnancies using computerized colposcopy. All patients had baseline computer‐assisted measurements of their cervical lesions and a repeat measurement at monthly intervals and at 3‐months postpartum. Results. During the period of gestation, 17.1% of lesions increased in size, 21.9% remained unchanged, 41.5% decreased in size and 19.5% disappeared completely. In patients with an increase in lesion size, a colposcopically directed punch biopsy was performed which revealed CIN III but no microinvasion. Cervical biopsy during pregnancy was unnecessary in 82.9% of cases. Conclusion. The ability to sequentially monitor and quantify colposcopically visualized lesions, using computerized colposcopy, provides a noninvasive objective mode to evaluate progression, stability, or regression of CIN lesions during pregnancy.