Open AccessPerinatal outcome after in vitro fertilisation
Author(s) -
Petersen Karsten,
Hornnes Peter J.,
Ellingsen Susanne,
Jensen Flemming,
Brocks Vibeke,
Starup Jørgen,
Jacobsen Joes Ramsøe,
Andersen Anders Nyboe
Publication year - 1995
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349509008921
Subject(s) - medicine , obstetrics , singleton , in vitro fertilisation , infertility , gestation , birth weight , gynecology , pregnancy , multiple birth , gestational age , incidence (geometry) , embryo transfer , low birth weight , population , genetics , physics , environmental health , optics , biology
A prospective series of 90 consecutive pregnancies (70 singleton, 16 twin and 4 triplet pregnancies) resulting in births of 114 infants after in vitro fertilisation (IVF) at Rigshospitalet were compared to a control group of pregnancies and deliveries in 70 non‐IVF infertility patients with singleton pregnancies and 20 women with normal fertility with twin ( n =16) or triplet ( n =4) pregnancies. No differences in the incidence of third trimester pregnancy complications, abnormal fetal karyotypes or malformations were found. The number of women with spontaneous onset of labor and the gestational age at delivery were similar in the IVF and control groups. In singleton deliveries, the birth weight was lower ( p <0.025) in the IVF group (median 3145 g, range 8904300 g) than in the control group (3399 g, 2592–4850 g), whereas in multiple gestation similar birth weights were found in the IVF and control groups. We conclude that the birth weight in singleton deliveries after IVF is lower than the birth weight in infertility patients treated differently. The cause of this difference remains obscure.