Open AccessEndometriosis in monozygotic twins
Author(s) -
Moen Mette H.
Publication year - 1994
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349409013396
Subject(s) - endometriosis , medicine , laparotomy , laparoscopy , proband , adenomyosis , obstetrics , monozygotic twin , medical record , gynecology , sister , surgery , genetics , mutation , sociology , biology , anthropology , gene
Objective . To study the reproductive and medical history of monozygotic twin sisters and mothers of patients with endometriosis. Material and methods . Among 515 patients with endometriosis, eight had a monozygotic twin sister all of whom had had a gynecological laparoscopy or laparotomy. In addition, five of their mothers had had a laparotomy. Details about these 13 relatives were obtained either from medical records (ten cases) or by unmistakable reports from the proband (three cases). Result . Six of the monozygotic twin sisters (75%) also had symptomatic endometriosis compared with 3.8% among other types of sisters ( p < 0.0005). Three of the mothers (38%) had either endometriosis or adenomyosis. Conclusion . This study gives support to the assumption that endometriosis has a genetic trait.