Open AccessA possible effect of ultrasound on RNA synthesis in cultured amniocytes
Author(s) -
Zur Orit,
Shneyour Yona,
Dan Uzi,
Chemke Juan,
Shneyour Amir,
Shalev Eliezer
Publication year - 1993
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349309068031
Subject(s) - rna , ultrasound , medicine , fetus , uridine , microbiology and biotechnology , biochemistry , biology , pregnancy , genetics , gene , radiology
The effect of both diagnostic and therapeutic ultrasound on cellular RNA synthesis was investigated in amniocytes cultured in F‐10 medium enriched with fetal calf serum. The rate of RNA synthesis was tested using incorporation of H 3 uridine, which was added following the exposure to acid insoluble RNA. Cultured amniocytes which were not exposed to ultrasound served as the control. Different results were obtained following the two ranges of exposure. A significant decrease in RNA synthesis was demonstrated immediately following diagnostic ultrasound and a certain increase in RNA synthesis was demonstrated soon after exposure to therapeutic doses. These effects were transient and could not be shown 24 hours later. It is concluded that the routine use of ultrasound can not have any clinical implications on RNA synthesis.