Open AccessManagement of vulvar carcinoma radiation toxicity, results and failure analysis in 44 patients (1980–1989)
Author(s) -
SnijdersKeilholz Tonny,
Trimbos J. Baptist,
Hermans Jo,
Leer Jan Willem H.
Publication year - 1993
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349309021162
Subject(s) - medicine , radiation therapy , surgery , vulva , carcinoma , vulvar cancer , retrospective cohort study , toxicity
A retrospective analysis was performed on 44 patients with squamous carcinoma of the vulva (1980–1989). Patients were divided into two subgroups. group I (n = 39) treated with curative intent with surgery alone or with surgery combined with radiotherapy and group II (n = 5) treated with palliative intent with irradiation alone. The five‐year cancer‐specific survival rate for group I was 65%. Although this is a group of elderly patients. it was concluded that curative therapy should he aggressive and concessions which lead to suboptimal treatment should be avoided. It is essential to achieve free surgical margins. If it is decided to irradiate, no concessions should he made with respect to dose or overall treatment time. Poor results were obtained in the group treated with palliative intent with a six week treatment scheme of live fractions/wk. All irradiated patients suffered from moist desquamation as acute side‐effect. Serious late side‐effects did not occur.