Open AccessPlasma immunoglobulin, total protein and albumin levels during Norplant use by Nigerian women
Author(s) -
Otolorin E. O.,
Adeyefa I.,
Konje J. C.,
Ojengbede O.,
Osotimehin B.,
Ladipo O. A.
Publication year - 1993
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349309021158
Subject(s) - medicine , albumin , antibody , immunoglobulin g , endocrinology , obstetrics , immunology
Objective. To determine the effect of Norplant on plasma immunoglobulins, albumin and total proteins. Design A longitudinal prospective study of Norplant (six capsules) subdermal contraceptive implant acceptors. Setting. Family Planning Clinic. University College Hospital, Ibadan, Nigeria. Patients. 36 women volunteers aged 18–40 years on Norplant. Main outcome measures. Serum immunoglobulins, albumin and total protein before, one, three and 12 months after Norplant insertion. Results. No statistically significant changes were observed in plasma levels of IgA. IgM and total proteins hut plasma levels of IgG showed statistically significant increases after one, three and 12 months on Norplant. Conclusion Norplant does not seem to alter IgM, IgA. albumin and total protein levels over a period of 12 months. It, however, induces significant changes in IgG levels at one. three and 12 months after insertion. These changes are less marked by the end of 12 months.