
Cervical conization and preterm delivery/low birth weight
Author(s) -
Kristensen J.,
LanghoffRoos J.,
Wittrup M.,
Bock J. E.
Publication year - 1993
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349309021157
Subject(s) - medicine , cervical conization , preterm delivery , obstetrics , low birth weight , premature birth , gynecology , pregnancy , cervical cancer , cervical intraepithelial neoplasia , gestational age , gestation , cancer , biology , genetics
Objective. Evaluate the effect of cervical conization on preterm birth/low birth weight (LBW). Design. A systematic review of the literature using external or internal controls. Results. The typical odds ratio for preterm delivery in women with prior cervical conization using external controls was 3.23 (95% confidence interval 2.29–4.55). Using internal controls the typical odds ratio for LBW was 2.97 (95% confidence interval 1.09 8.05). Using external controls the typical odds ratio for LBW was 2.31 (95% confidence interval 1.33‐3.99). Conclusion. Women with cervical conization are at higher risk for preterm birth than external controls, and the surgical intervention as such is a major determining factor.