Open AccessIntraoperative evaluation of prognostic factors in stage I endometrial cancer by frozen section: how reliable?
Author(s) -
Zorlu C. Gurkan,
Kuscu Esra,
Ergun Yusuf,
Aydogdu Tugrul,
Cobanoglu Omer,
Erdas Orhan
Publication year - 1993
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349309021118
Subject(s) - medicine , frozen section procedure , paraaortic lymph nodes , lymphadenectomy , endometrial cancer , stage (stratigraphy) , cervical cancer , surgery , lymph node , radiology , hysterectomy , cancer , metastasis , paleontology , biology
The incidence of pelvic/paraaortic lymph node metastases is related to the grade of the tumor, the depth of myometrial invasion and the cervical involvement. These prognostic factors determine the initial surgery. Intraoperative evaluation and frozen section (FS) have been used for this purpose in order to identify patients requiring pelvic/paraaortic lymphad‐enectomy and adjuvant therapy, thereby eliminating routine lymphadenectomy with its complications. We used frozen section for this purpose and identified accurately 90% of patients requiring pelvic/paraaortic lymphadenectomy. The depth of myometrial invasion was accurately predicted in 90.6% and histologic grade in 91.9% of the patients; however, 60% of patients with cervical involvement were identified by FS. We recommend the use of frozen section as an inexpensive, simple and accurate way of estimating the poor prognostic factors.