Open AccessAnastomosis of uterine serosa with cyanoacrylate versus suture in rats
Author(s) -
CaballeroGómez J. M.,
OrtegaMoreno J.
Publication year - 1993
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349309013374
Subject(s) - cyanoacrylate , medicine , anastomosis , surgery , microsurgery , fibrous joint , uterine horns , surgical anastomosis , anatomy , uterus , adhesive , chemistry , organic chemistry , layer (electronics)
Experimental end‐to‐end uterine horn anastomosis was performed in 20 Wistar rats with the conventional technique of microsurgery, with n‐butyl‐cyanoacrylate and with cyanoacrylate with the addition of one or two microsutures. Only in the case of conventional anastomosis and of cyanoacrylate in combination with two microsutures, was the patency rate 100%, whereas in the case of uterine horns anastomosed with cyanoacrylate alone, the patency rate was 80%. Histologic findings revealed the presence of tissue adhesive encysted in the serosa with a moderate inflammatory reaction around it, remaining two months after surgery. On the 60th day, the muscularis layer was only continuous in the conventional and cyanoacrylate with two microsutures groups. Our findings indicate that tissue adhesive and two sutures used together may offer a viable alternative to sutures for genital duct anastomosis.