Open AccessThe coexistence of stromomyoma and uterine tumor resembling ovarian sex‐cord tumors: Report of a case and immunohistochemical study
Author(s) -
Erhan Ylldlz,
Baygün Mine,
Özdemir Necmettin
Publication year - 1992
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349209021080
Subject(s) - pathology , stroma , desmin , vimentin , mesenchyme , stromal cell , immunohistochemistry , keratin , medicine , biology , mesenchymal stem cell
The case of a 40‐year‐old female with a uterine tumor resembling an ovarian sex‐cord tumor, located within another neoplastic nodule having the histopathological features of a stromomyoma is reported. Light microscopic examination of the uterine sex‐cord‐like tumor revealed a highly cellular tumor tissue with no specific differentiation, consisting of solid nests and anastomosing cords and a few pseudo‐tubular structures. The vacuoleted cytoplasm of the lipid‐rich cells proved vimentin‐positive, but desmin‐ and keratin‐negative. The coexistence of the two variants of endometrial stromal tumor was interpreted as arising from endometrial stroma or multipotential uterine mesenchyme that showed a diverse differentiation toward ovarian sex‐cord stroma and uterine smooth muscle with interspersed stromal cell clusters.