Open AccessFetal death following labetalol administration in pre‐eclampsia
Author(s) -
Olsen Karsten Skovgaard,
BeierHolgersen Randi
Publication year - 1992
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349209007974
Subject(s) - labetalol , medicine , eclampsia , fetus , obstetrics , fetal death , pregnancy , anesthesia , blood pressure , biology , genetics
Labetalol (Trandate®) 50 mg i.v. was administered to a pre‐eclamptic primigravida with an asphytic fetus prior to cesarean section, in order to reduce the risk of excessive increase in blood pressure during induction of anesthesia. Blood pressure fell rapidly from 170/110 to 115/85 mmHg. A dead infant was born. Oral labetalol is arguably a suitable remedy for pre‐eclampsia, but if i.v. administration is necessary, an initial dose of 5–10 mg is recommended.