Open AccessFetal and infant outcome of pregnancies with very early rupture of membranes
Author(s) -
Montan Sven,
Holmquist Peter,
Ingesson Karin,
Ingemarsson Ingemar
Publication year - 1991
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349109006192
Subject(s) - medicine , fetus , obstetrics , pregnancy , outcome (game theory) , gynecology , genetics , biology , mathematics , mathematical economics
Fetal and infant outcome was studied in 38 singleton pregnancies complicated by very early rupture of membranes (PROM), in gestational weeks 19‐29, over a 4‐year period, in a Swedish population. The pregnancies were managed according to a specified protocol, including postponement of delivery until 34 weeks of gestation if possible. Stillbirth occurred in 10 cases (26.3%), all with PROM before 26 completed weeks, while 6 other infants died in the neonatal period. Respiratory distress syndrome was evident in half (50.0%) of the 28 liveborn infants. The surviving 22 infants (57.9%) were followed up to 2 years of age. The rate of neurological sequelae at follow‐up was 22.7 % (5/22). The fetal outcome of the 20 pregnancies with rupture of membranes before 26 completed weeks was poor; only 7 infants of the 10 born alive survived the neonatal period. The short‐term fetal outcome in the group with rupture of membranes in 26‐29 completed weeks was better: 15 of the 18 infants survived, but 4 had neurological sequelae. PROM before 29 completed weeks of gestation is associated with severe short‐term and long‐term fetal complications, in cases where the pregnancy is prolonged for several weeks.