Open AccessIontophoresis of vasoactive drugs Effect on peripheral blood flow during pregnancy
Author(s) -
EnerothGrimfors Eva,
Lindblad LarsErik,
Westgren Magnus,
Etzell BrittMarie,
Bevegård Sture
Publication year - 1991
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349109006173
Subject(s) - medicine , iontophoresis , vasoactive , blood flow , laser doppler velocimetry , angiotensin ii , pregnancy , eclampsia , anesthesia , hemodynamics , obstetrics , blood pressure , radiology , genetics , biology
The aim of this study was to evaluate whether iontophoretic administration of the vasoactive agents noradrenalin (NA) and angiotensin (AII) combined with measurement of skin blood flow with a laser Doppler technique could serve as a predictive method for pre‐eclampsia. Nine healthy non‐pregnant women, 9 healthy pregnant women and 9 pre‐eclamptic patients were investigated. A significant reduction of skin blood flow was induced by NA in all three groups and by AII in the non‐pregnant group. There was no significant difference between healthy pregnant and pre‐eclamptic patients in the degree of reduction of blood flow with respect to NA and All administration.