Open AccessPeripheral and Ovarian Venous Concentrations of Estradiol and Progesterone in Postmenopausal Women with “Non‐Endocrine” Ovarian Tumors
Author(s) -
Kitayama Shunya,
Nakano Ryosuke
Publication year - 1990
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349009028688
Subject(s) - medicine , venous blood , menopause , ovary , endocrine system , peripheral , peripheral blood , ovarian cancer , estrogen , hormone , endocrinology , cancer
Estradiol (E 2 ) and progesterone (P 4 ) levels in peripheral venous blood were measured in 45 postmenopausal (more than 5 years after menopause) women with ovarian neoplasms. The E 1 and P 4 concentrations in ovarian venous blood were also measured in 26 of these 45 patients. The steroid levels were compared with the values in 10 postmenopausal women without ovarian tumors. In peripheral venous blood, relatively high E, concentrations were found in 24 of the 45 (53%) postmenopausal patients with ovarian tumors, and relatively high P 4 concentrations were noted 15 of 45 (33%) of the patients. In ovarian venous blood, relatively hgih values of E 2 were found in 18 of 26 (69%) of the postmenopausal patients, and relatively high values of P 4 were noted in 11 of these 26 (42%). No differences in the E, and P 4 levels in peripheral and ovarian venous blood were noted between the patients with benign tumors and those with malignant tumors. These results suggest that some of the epithelial ovarian tumors in postmenopausal women have steroid‐producing activity.