Open AccessPhysiological Values of Cystein and Metalloproteinase Activities in Chorionic Villi
Author(s) -
Láaszlóa Aranka,
Sonáar Istváan,
Falkay Gyoürgy,
Kováacs Attila,
Halmos Viktóaria,
Szabóa Jáanos
Publication year - 1990
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016349009013300
Subject(s) - chorionic villi , cathepsin , cathepsin b , cathepsin d , cathepsin l , andrology , medicine , enzyme , microbiology and biotechnology , endocrinology , pregnancy , biochemistry , biology , fetus , placenta , genetics
Lysosomal cysteine proteinases (cathepsin H, B + L) and metallopro‐teinase (MMP7‐ase) activities were measured from early gestational period (6‐12 weeks) in frozen, non‐cultivated chorionic villi. The mean activity of cathepsin H was 50.99 mU/mg protein, of cathepsin B + L, 71.16 mU/mg protein, and of MMP7‐ase, 16.16 mU/mg protein. The MMP7‐ase enzyme activities showed a correlation with gestational age. There was a significant correlation between the activities of cathepsin H and MMP7‐ase.