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Heterophilic Antibodies Against Rabbit Serum Causing Falsely Elevated Gonadotropin Levels
Author(s) -
Berglund Lars,
Holmberg NilsGunnar
Publication year - 1989
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348909028676
Subject(s) - medicine , human chorionic gonadotropin , antibody , hormone , gonadotropin , rabbit (cipher) , follicle stimulating hormone , endocrinology , equine chorionic gonadotropin , andrology , immunology , luteinizing hormone , ovulation , statistics , mathematics
Two cases are presented in which previously acquired antibodies against rabbits in the patient's serum caused falsely elevated hormonal levels in radio‐irnmuno assays (RIA) based on rabbit antibodies to follicle‐stimulating hormone (FSH) and human chorionic gonadotropin (hCG). The erroneous results led to unnecessary operative intervention and inconvenience for the patients.