Open AccessEffect Of β‐Receptor Blockers On Uterine Contractility In A Puerperal Model
Author(s) -
Egarter Ch.,
Meisner W.,
Kroboth W. K.,
Grünberger W.
Publication year - 1989
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348909028672
Subject(s) - medicine , myometrium , pindolol , placebo , pregnancy , contractility , uterus , nifedipine , gynecology , receptor , endocrinology , obstetrics , calcium , pathology , biology , genetics , alternative medicine
β‐receptor blockers are increasingly used in the treatment of pregnancy‐induced hypertension. Hitherto an oxytocic effect on the myometrium could not be excluded. We investigated the effect of 0.8 resp 1.6 mg pindolol on uterine activity in a double blind study in comparison with a placebo group, using a puerperal model. A “paradoxical” decline in uterine activity could be demonstrated, speaking in favor of a further propagation of β‐blockers in obstetric practice.