Open AccessFetal Growth And Fetal Glucose And C‐Peptide Levels In Relation To The Degree Of Anemia In Fetuses Affected By Rhesus Iso‐Immunization
Author(s) -
Westgren Magnus,
Selbing Anders,
Stangenberg Magus
Publication year - 1989
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348909028664
Subject(s) - fetus , medicine , hemoglobin , fetal hemoglobin , fetal growth , endocrinology , rh isoimmunization , pregnancy , anemia , biology , genetics
Fetal growth rate was determined by measuring the fetal biparietal diameter at 63 two‐week time points during the second trimester in 14 patients with severe Rhesus isoimmunization. Growth rate was found to be related to the fetal hemoglobin concentration which was determined at the end of each 2‐week period. Fetuses with a hemoglobin concentration of less than 30% of the normal value had a significantly decreased growth rate (p<0.01). These fetuses had also reduced C‐peptide (p<0.05) and increased glucose levels (p<0.1) compared with less anemic fetuses. The physiological background to impaired fetal growth in cases of severe fetal anamia at Rhesus iso‐immunization is discussed.