Open AccessPlacental Proteins 12 And 14 In Pre‐Eclampsia
Author(s) -
Howell R. J. S.,
Economides D.,
Teisner B.,
Farkas A. G.,
Chard T.
Publication year - 1989
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348909020995
Subject(s) - decidua , medicine , eclampsia , preeclampsia , placenta , endocrinology , pregnancy , fetus , biology , genetics
The concentrations of circulating placental protein 12 (PP12) and placental protein 14 (PP14) were measured in 41 patients with pre‐eclampsia and in 17 control subjects. The levels of PP12 were significantly elevated in patients with severe pre‐eclampsia, whereas PP14 levels were unaffected. There was a negative correlation between the levels of both PP12 and PP14 and birthweight. PP12 and PP14 appear therefore to have different control mechanisms and, possibly, different cellular origins within the decidua.