Open AccessUrinary Iodine Excretion is Low and Serum Thyroglobulin High in Pregnant Women in Parts of Denmark
Author(s) -
Pedersen Klaus M.,
Borlum Karl G.,
Knudsen Preben R.,
Hansen EdvinSteen,
Johannesen Peter L.,
Laurberg Peter
Publication year - 1988
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348809004251
Subject(s) - iodine , medicine , pregnancy , creatinine , thyroglobulin , excretion , iodine deficiency , endocrinology , urinary system , physiology , thyroid , chemistry , genetics , organic chemistry , biology
In the Randers area of Denmark urinary iodine excretion (which reflects iodine intake) was found to be much lower than recommended intake levels, both in women in late pregnancy [52(23–118) pg iodine/g creatinine, median, range, n = 20] and in non‐pregnant controls [42(23–711, n = 20]. Serum thyroglobulin which is high in iodine deficiency was 32.5 pgA (median) (range 10.5–78.0) in the control women and considerably higher in the pregnant women [67.0 pgll (9.0–385)]. This increase was probably due to the extra iodine requirement of pregnancy which was not satisfied with an adequate increase in iodine intake. The results may suggest that pregnant women in this area should receive iodine supplementation and that a general program of iodine supplementation should be considered.