Open AccessEthinylestradiol and Desogestrel, Alone or in Combination with two Doses of Estriol: Effects on plasma proteins
Author(s) -
Cullberg Göran,
Mattsson LarsÅke
Publication year - 1988
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348809004192
Subject(s) - ethinylestradiol , desogestrel , estriol , medicine , transcortin , endocrinology , globulin , sex hormone binding globulin , research methodology , estrogen , hormone , population , family planning , androgen , environmental health
. Nineteen fertile women were treated with three differently composed oral contraceptives in a cross‐over study and were randomly allocated to begin with one of the three preparations The tablets contained 0030 mg ethinylestradiol + 015 mg desogestrel alone (A) or in Combination with either 05 mg estriol (B) or 2 mg estriol (CI After two treatment cycles on each preparation, blood samples were obtained and analysed for ceruloplasmin, SHBG, prealbumin, transcortin and thyroxine‐binding globulin No differances were found in the induction of liver protein synthesis It was concluded that the addition of estriol in doses of 05 or 2 mg did not influence the effects induced by ethinylestradiol.