Open AccessReconstructive Microsurgery of the Rabbit Oviduct Using Serosal Microsutures and Fibrin Sealant
Author(s) -
Sørensen SÓRen Stampe,
Schroeder Erik,
Olesen Henning Peter
Publication year - 1987
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348709022060
Subject(s) - medicine , microsurgery , fibrin , oviduct , sealant , rabbit (cipher) , surgery , andrology , immunology , statistics , mathematics , chemistry , organic chemistry
Microsurgical reconstruction of the rabbit oviduct was undertaken utilizing either: A: fibrin sealant in a thick layer applied to two or three serosa microsutures (20 rabbits), B: fibrin sealant only (20 rabbits), and C: microsutures only (20 rabbits). The pregnancy rates and the patency rates of the oviducts showed no significant differences between the three groups. However, the formation of adhesions at the site of re‐anastomosis was significantly lower and the total duration of surgery significantly shortened when fibrin sealant was employed. It is concluded that fibrin sealant combined with serosa microsutures certainly is the most convenient method in human tubal microsurgery seeing that this method maintains a higher tensil strength at the site of reanastomosis as compared to group B and avoid the risk of mucosal lesions as compared to group C. out using a clamp to approximate the tube ends, and instead to place two or three microsutures in the serosal layer before covering the anastomosis by fibrin sealant. Moreover, the risk of spontaneous rupture of the anastomosis between the 2nd and the 4th day after surgery, as with fibrin adhesive alone, would certainly be minimized. Accordingly the present investigation was initiated in the hope of achieving the same high pregnancy and oviduct patency rates and the same low formation of adhesions and short operation time as for anastomosis with fibrin sealant alone when compared with anastomosis by PGA microsutures.