Open AccessThe prognostic significance of virus‐associated changes in grade 1 cervical intraepithelial neoplasia
Author(s) -
Bagi Per,
Worning Anne Marie,
Nordsten Merete,
Berget Arne,
Badsberg Edith
Publication year - 1987
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348709022051
Subject(s) - medicine , cervical intraepithelial neoplasia , virus , cervix , persistence (discontinuity) , gastroenterology , cervical cancer , immunology , cancer , geotechnical engineering , engineering
Virus‐associated changes of the cervix uteri were assessed in patients treated for grade 1 cervical intra‐epithelial neoplasia (CIN). Of 106 patients evaluated, 67 (63%) had virus‐associated changes. The patients were treated without regard to the presence/abscence of virus‐associated changes. In 26 patients the treatment was unsuccessful (persistence, recurrence, or progression of the neoplasia). The frequency of treatment failure was 33% in patients with, and 10% in patients without virus‐associated changes (p < 0.025). It is recommended that patients with CIN 1 and virus‐associated changes should, after initial treatment, be followed‐up with increased attention.