Open AccessTheca Lutein Cysts with Maternal Virilization and Elevated Serum Testosterone in Pregnancy
Author(s) -
Ito Masaharu,
Tohya Toshimitsu,
Yoshimura Toshihiro,
Matsui Kazuo,
Fujisaki Shunichi,
Okamura Hitoshi
Publication year - 1987
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.3109/00016348709015737
Subject(s) - virilization , theca , medicine , testosterone (patch) , pregnancy , lutein , fetus , corpus luteum , immunoperoxidase , endocrinology , andrology , ovary , gynecology , hormone , androgen , biology , immunology , botany , antibody , monoclonal antibody , carotenoid , genetics
A clinicopathological study was performed on a pregnant patient with bilateral multiple ovarian cysts, who presented with pre‐eclampsia, marked virilization and exceedingly high levels of serum testosterone. The female fetus showed no evidence of virilization. Microscopic examination of the ovaries revealed theca lutein cysts with granulosa cells which showed the existence of testosterone by immunoperoxidase staining.